- The Tourist (2010)- Elise
- Salt (2010)- Evelyn Salt
- Wanted (2008)- Fox
- Changeling (2008)- Christine Collins
- Kung Fu Panda (2008)- Tigress (voice)
- Beowulf (2007)- Grendel’s Mother
- A Mighty Heart (2007)- Mariane Pearl
- The Good Shepherd (2006)- Margaret ‘Clover’ Russell
- Mr. & Mrs. Smith (2005)- Jane Smith
- Alexander (2004)- Olympias
- The Fever (2004)- Revolutionary
- Sky Captain and the World of Tomorrow (2004)- Franky
- Shark Tale (2004)- Lola (voice)
- Taking Lives (2004)- Illeana
- Beyond Borders (2003)- Sarah Jordan
- Lara Croft Tomb Raider: The Cradle of Life (2003)- Lara Croft
- Life or Something Like It (2002)- Lanie Kerrigan
- Original Sin (2001)- Julia Russell / Bonny Castle
- Lara Croft: Tomb Raider (2001)- Lara Croft
- Gone in Sixty Seconds (2000)- Sara ‘Sway’ Wayland
- Girl, Interrupted (1999)- Lisa Rowe
- The Bone Collector (1999)- Amelia Donaghy
- Pushing Tin (1999)- Mary Bell
- Playing by Heart (1998)- Joan
- Hell’s Kitchen (1998)- Gloria McNeary. An alternate title of the film is ‘Hell’s Kitchen N.Y.C’
- Gia (1998: television movie)- Gia Carangi
- Playing God (1997)- Claire. An alternate title of the film is ‘Playing Hero’.
- George Wallace (1997: TV movie)- Cornelia Wallace
- True Women (1997: TV movie)- Georgia Virginia Lawshe Woods
- Foxfire (1996)- Legs Sadovsky
- Mojave Moon (1996)- Eleanor ‘Elie’ Rigby
- Love Is All There Is (1996)- Gina Malacici
- Hackers (1995)- Kate Libby / ‘Acid Burn’
- Without Evidence (1995)- Jodie Swearingen
- Cyborg 2 (1993)- Casella ‘Cash’ Reese. The US DVD title is ‘Glass Shadow’.
- Alice & Viril (1993)- Alice
- Angela & Viril (1993)- Angela
- Lookin’ to Get Out (1982)- Tosh. Angelina appears as ‘Angelina Jolie Voight- her birth name.